Matteo Magri
Structural Biology, Synchrotron Science & Computational Biophysics
Investigating macromolecular architecture and dynamics at the intersection of European synchrotron facilities and computational simulation. Focused on beamline experimentation, quantum mechanics/molecular mechanics (QM/MM), and open-source scientific software.
About Me
I am a scientist based at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France, actively engaged with the Joint Structural Biology Group (JSBG).
My research lies at the nexus of high-brightness synchrotron X-ray techniques and modern computational biophysics. I combine structural biology workflows—such as macromolecular crystallography and automated beamline processes—with computational molecular modeling (hybrid QM/MM calculations, molecular dynamics, and electronic structure simulations).
Beyond the wet lab and beamline floor, I develop reproducible scientific software, data analysis scripts, and automation pipelines in Python and Fortran to facilitate rigorous, open science.
Overview
- Affiliation ESRF • JSBG
- Location Grenoble, France
- Core Focus Structural Biology & QM/MM
- Languages Python, Fortran, C++
- GitHub @MatteoMagri
- ORCID 0009-0004-0390-3800
Research & Focus Areas
Combining state-of-the-art synchrotron instrumentation with theoretical and computational frameworks.
Synchrotron Structural Biology
Macromolecular crystallography, automated sample screening, X-ray diffraction, and beamline operations tailored for structural determination of complex biological systems.
QM/MM & Molecular Dynamics
Quantum mechanical / molecular mechanics simulations, DFT electronic calculations, force field parametrization, and trajectory analysis of enzymatic reaction mechanisms.
Scientific Computing & Tools
Building lightweight, reproducible Python libraries, computational pipelines, structural batch processors, and automated workflows for scientific research.
Selected Projects
Open-source software, datasets, and utilities hosted on GitHub.
Curated repository and image records of macromolecular crystals, crystallization outcomes, and photographic observations for crystallography studies.
Systematic pH calculation package for Python. Resolves exact equilibrium concentrations and pH in arbitrary acid/base/salt mixture systems.
Fast, intuitive Mandelbrot set rendering and numerical fractal exploration library written in Python.
Tools, test sets, and scripts for working with macromolecular PDB files, structural validation, coordinate transformations, and data preprocessing.
Get in Touch
Feel free to connect for scientific discussions, synchrotron research, or collaboration.